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Nebula genomics its will closed in 4 February 2025
#16
(01-22-2025, 11:37 PM)miquirumba Wrote:
(01-22-2025, 09:53 PM)mjaguk Wrote: DNA Complete website ( https://dnacomplete.com/about-us/ ) says this:

"DNA Complete is powered by a pioneer in genomics. Our sister company and lab partner Nebula Genomics is trusted by more than 100,000 satisfied customers across more than 130 countries. Our founder, Dr. George Church, has been a leader in personal genomics for decades.....
DNA Complete is powered by Nebula Genomics, a division of ProPhase Labs. ProPhase Labs is a publicly traded, next-generation biotech, genomics, and diagnostics company on a mission to create a healthier world through bold action and the power of insight.
The company operates a state-of-the-art, 30,000-square-foot whole genome sequencing lab facility in the U.S. It is one of the largest whole genome sequencing laboratories in the U.S."

This is what Nebula is saying:

"Important Announcement
Nebula Genomics Membership Transition
Nebula Genomics will soon be shutting down.
But don’t worry - this is the start of something even better. We’re thrilled to introduce
DNA Complete
A next-generation service enhanced with a number of new, cutting-edge features to take your genetic insights further.
Take Action Today: Transition to DNA Complete and continue unlocking the power of your DNA."

and Will DNA Complete go on Yfull haplogroup transfer? 
it seems that WGS labs from America want to cut off genealogic costumers, all WGS labs (Sequencing, Nucleus, DNA Complete) are focused on biomedical research

About Yfull , isn't seems to me this will effect a people was test in Nebula and upload result to Yfull
Target: CapsianWGS_scaled
Distance: 1.2510% / 0.01251049
37.2 Iberomaurusian
36.8 Early_European_Farmer
12.8 Early_Levantine_Farmer
8.0 Steppe_Pastoralist
4.8 SSA
0.4 Iran_Neolithic
FTDNA : 91% North Africa +<2% Bedouin + <2  Southern-Levantinfo + <1 Sephardic Jewish + 3% Malta +  3%  Iberian Peninsula
23andME :  100% North Africa

WGS ( Y-DNA and mtDNA)
Y-DNA: E-A30032< A30480 ~1610 CE
mtDNA: V12
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#17
(01-23-2025, 08:53 AM)Capsian20 Wrote:
(01-22-2025, 11:37 PM)miquirumba Wrote:
(01-22-2025, 09:53 PM)mjaguk Wrote: DNA Complete website ( https://dnacomplete.com/about-us/ ) says this:

"DNA Complete is powered by a pioneer in genomics. Our sister company and lab partner Nebula Genomics is trusted by more than 100,000 satisfied customers across more than 130 countries. Our founder, Dr. George Church, has been a leader in personal genomics for decades.....
DNA Complete is powered by Nebula Genomics, a division of ProPhase Labs. ProPhase Labs is a publicly traded, next-generation biotech, genomics, and diagnostics company on a mission to create a healthier world through bold action and the power of insight.
The company operates a state-of-the-art, 30,000-square-foot whole genome sequencing lab facility in the U.S. It is one of the largest whole genome sequencing laboratories in the U.S."

This is what Nebula is saying:

"Important Announcement
Nebula Genomics Membership Transition
Nebula Genomics will soon be shutting down.
But don’t worry - this is the start of something even better. We’re thrilled to introduce
DNA Complete
A next-generation service enhanced with a number of new, cutting-edge features to take your genetic insights further.
Take Action Today: Transition to DNA Complete and continue unlocking the power of your DNA."

and Will DNA Complete go on Yfull haplogroup transfer? 
it seems that WGS labs from America want to cut off genealogic costumers, all WGS labs (Sequencing, Nucleus, DNA Complete) are focused on biomedical research

About Yfull , isn't seems to me this will effect a people was test in Nebula and upload result to Yfull
only a little percentage of Nebula's transfers to Yfull have paid unlock since years ago, therefore, all these costumers have lost privilege to direct transfer from Nebula database, they and new DNA Complete costumers will must upload their chrY.bam and chrM.fasta (or bam) directly like sequencing.com costumers. Yfull always takes control about raw data after paying unlock, nothing to fear about unlocked kits
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#18
Y-DNA services are still outlandishly pricey, I'm not surprised it will remain very niche to most people since nobody is really willing to invest 4-500 euros for such a test. Perhaps when the price cuts in half or around the 100 euro mark then people will finally start also doing this test.
mjaguk, Capsian20, BowFX like this post
Ancient (Davidski's G25)
1. Western Steppe Herder 47.2%
2. Early European Farmer 39%
3. Western Hunter-Gatherer 11.6%
4. Han 2.2%

Modern World Regions (G25)
1. Eastcentral European 65%
2. West European 15.6 %
3. East Finnish 9.2%
4. Northwest Caucasian 9%
5. Hawaiian 1.2%
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#19
They aren't really closing, just rebranding as DNAComplete. The old Dante Labs trick? It comes after they got into some legal trouble https://www.reuters.com/legal/litigation...024-10-11/

(01-22-2025, 03:35 PM)AimSmall Wrote: You'd think by now full genome testing would be a commodity and readily available.  Pay your $100 and wait a week to download.  Nothing magic about it anymore.
Yeah, we haven't got the $100 genome we were promised years ago. Prices have stayed the same for the last 7-8 years or if anything they went up. Dante Labs when on sale was the closest but that might be gone now too.
mjaguk likes this post
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#20
(01-23-2025, 11:49 AM)Mythbuster General Wrote: Y-DNA services are still outlandishly pricey, I'm not surprised it will remain very niche to most people since nobody is really willing to invest 4-500 euros for such a test. Perhaps when the price cuts in half or around the 100 euro mark then people will finally start also doing this test.

you are right , the Y-DNA test (whether Y-Big700 or WGS) is very expensive
mjaguk likes this post
Target: CapsianWGS_scaled
Distance: 1.2510% / 0.01251049
37.2 Iberomaurusian
36.8 Early_European_Farmer
12.8 Early_Levantine_Farmer
8.0 Steppe_Pastoralist
4.8 SSA
0.4 Iran_Neolithic
FTDNA : 91% North Africa +<2% Bedouin + <2  Southern-Levantinfo + <1 Sephardic Jewish + 3% Malta +  3%  Iberian Peninsula
23andME :  100% North Africa

WGS ( Y-DNA and mtDNA)
Y-DNA: E-A30032< A30480 ~1610 CE
mtDNA: V12
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#21
Looks like DNAComplete/Nebula has some big sales going on right now in tandem with their rebrand:

https://dnacomplete.com/tier-selection/

The Pro Test looks intriguing to me since it's 30x coverage, which seems to be the standard sequencing I see in most academic papers, is the Elite 100x product just marketing overkill or would you actually get that much more insight out of the test compared to only 30x?

Are there are any current good competitors to Nebula/DNAComplete or are they pretty much still the only game in town for commercial WGS?
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#22
(01-27-2025, 01:42 PM)Horatio McCallister Wrote: Looks like DNAComplete/Nebula has some big sales going on right now in tandem with their rebrand:

https://dnacomplete.com/tier-selection/

The Pro Test looks intriguing to me since it's 30x coverage, which seems to be the standard sequencing I see in most academic papers, is the Elite 100x product just marketing overkill or would you actually get that much more insight out of the test compared to only 30x?

Are there are any current good competitors to Nebula/DNAComplete or are they pretty much still the only game in town for commercial WGS?

They may have sales but not good prices.

However, if somebody go for 100x, they would be the only option.
100x gives better chance to have sequenced the whole just 100% genome, I mean less chance to have no calls.

I would see what's going on on sequencing.com , I am pretty sure they had 200$ bargain lately.
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#23
Sequencing.com prices look comparable to DNAComplete, they are advertising huge discounts but not sure if that's just a marketing gimmick. Looks like all their products are 30x sequencing.

https://dna.sequencing.com/shop-all-bundles/


So does anyone have experience with either of these companies, who's the best for WGS in general?
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